Endocrine Abstracts

Objective: To create a national register of prolactin-secreting pituitary adenomas to assess the prevalence of various forms and the effectiveness of therapy.Material and research methods: National register of patients with pituitary prolactinomas in the Republic of Uzbekistan, includes 172 cases with pituitary prolactinomas, of which 61% (105 women) and 37.2% (64 men), aged 17-74 years, mean age 38.5 ± 12.6 years and 3 (1.7%) children and adolescents...

Aim: The work was initiated to study prolactin levels in hormonally inactive pituitary adenoma by the size of the tumor.Material and methods: We examined 85 patients with hormonally inactive pituitary adenomas, 45 women and 40 men among them aged from 18 to 50 years (mean age 44.5±3.85 years). The disease duration from the onset to diagnosis based on the medical history and MRI ranged from 1 to 15 years.Results and discussion:...

Objective: Evaluate effect of hyperprolactinemia on breast’s conditions.Methods: Investigated 2 groups of patients with average age 34.9±7.5. The first group is 30 women with hyperprolactinemia. Inclusion criterion was an increase in prolactin level above 1000 mU/l with a double determination, as well as duration of at least 6 month, lack of taking antidepressants and oral contraceptives for last 3 month before the start of study, absence of co...

Purpose: To assess the effect of radiation therapy (RT) in patients with acromegaly, depending on the age of the patients and the activity of the formation.Materials and methods: The object of the study was 50 patients (36 women and 14 men) with acromegaly who received gamma-therapy in a total dose of 45-60 Gr. The age of patients ranged from 29 to 77 years. By age, the patients were divided into 3 groups: 1st age group-29–44years old-23patients (46...

Aim: To study the course of clinical symptoms in women with prolactinomas.Material and research methods: The study included the results of clinical examination and treatment of 73 patients with prolactin-secreting pituitary adenomas. In the main group, 84.9% (62 women) and 15.1% (11 men) aged from 17 to 74 years old, the average age was (38.5±12.6 years). All patients were divided into 2 groups depending on the size of the education. Group I consist...

Aim: The work was initiated to study prolactin levels in hormonally inactive pituitary adenoma by the size of the tumor.Material and methods: We examined 85 patients with hormonally inactive pituitary adenomas, 45 women and 40 men among them aged from 18 to 50 years (mean age 44.5±3.85 years). The disease duration from the onset to diagnosis based on the medical history and MRI ranged from 1 to 15 years.Results and discussion:...

Purpose: To assess the sensitivity and specificity of the cytomorphological method in the diagnosis of the nosological variant of nodal goiter.Materials and methods: A comparison of the results of cytological and histological studies of thyroid nodules in 36 patients (15 women and 11 men, average age 54.2±9 years), operated for nodular goiter. Cytological findings were divided into 4 categories: ‘non-informative material’, ‘benign les...